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The model recapitulates many of the clinical features observed in patients living with BBS5 and sheds light on adipocyte biology, as well as the hypothalamic mechanisms driving hunger- and food-seeking behaviors that fuel the adverse metabolic phenotype

doi: 10.3389/fphar.2025.1689575 Received 20 August 2025 Revised 22 October 2025 Accepted 27 October 2025 Published 21 November 2025 Volume 16 - 2025 Edited by Mamunur Rashid, University of Nebraska Medical Center, United States Reviewed by Franois Trottein, Institut Pasteur de Lille, France Yunlei Zhang, Nanjing Medical University, China Updates Copyright 2025 Ruan, Lin, Lin, Zhan, Zheng, Lin, Zhuang and Zeng

Learn more Lab Tests in This Article References Anderson, S

Effective management of bowel changes during tirzepatide therapy involves both preventive strategies and symptomatic interventions