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Scientific References Teichman SL, Neale AR, Lawrence B, Gagnon C, et al

Because of its glucagon activation, Retatrutide may help sustain metabolic rate even after significant weight loss potentially reducing the yo-yo effect often seen when metabolism slows with dieting alone

In receptor binding studies, the affinity of tirzepatide was comparable to that of native GIP for the GIP receptor and approximately fivefold weaker than that of native GLP-1 for the GLP-1 receptor [88]

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