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In a larger study of mice expressing HIP, no evidence of pancreatitis was seen in mice given sitaglyptin for 1 year (4)
GCN2 phosphorylates eIF2, leading to ATF4 induction and upregulation of downstream targets including CHAC1
declares funding to conduct clinical trials from AstraZeneca, Bayer, Boehringer Ingelheim and Novo Nordisk (all to the INCLIVA Research Institute)
This article shows how central insulin action controls food intake and body weight
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