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This zone comprises the glycocalyx, plasma membrane, surface-connected canalicular system, membrane receptors (e.g., integrins, glycoprotein Ib-IX-V), and the submembrane cytoskeleton [25]

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SDP has received research funding from AstraZeneca, Boehringer Ingelheim, Novartis Pharmaceuticals Co., and Merck Sharpe & Dohme, and is a consultant for or has received honoraria from AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, GlaxoSmithKline, Janssen Pharmaceuticals, Laboratoires Servier, Merck Sharp & Dohme, Novartis Pharmaceuticals Co., Novo Nordisk, Sanofi, and Takeda

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