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Moreover, because LAL activity is implied in the pathophysiology of atherosclerosis as well, systemic treatment with recombinant LAL in mouse models has proven beneficial by reducing the size of atherosclerotic plaques, as reviewed elsewhere (111)
In October 2024, the ASA released updated multisociety guidance that shifted toward a risk-stratified approach, emphasizing prolonged fasting and optional use of POCUS instead of blanket medication withholding [10]
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Understanding semaglutide onset timelines and discontinuation considerations helps researchers who might transition between single and combined protocols
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