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For context, the fat-mass reductions reported in Billon 2024 roughly 25-30% in diet-induced obese mice over 28 days without exercise are large for a preclinical metabolic agent and explain why the "exercise mimetic" label stuck

The Melbourne-based company, which does not manufacture the drug, claims it is a potential treatment for cartilage and muscle damage and even osteoarthritis, though there is absolutely no clinical evidence of that

Shaking creates shearing forces that can denature the peptide, rendering it useless

Some of the most common symptoms of vitamin B12 deficiency are fatigue, memory issues, insomnia, stomach issues, etc