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We hypothesize that conformer 1 is required for G protein activation, and that adoption of this receptor conformation is favored under conditions used to form a stable complex that can be imaged (inclusion of dominant negative G protein and nanobody 35, apyrase treatment)
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In various models, GIP seems to stimulate LPL activity (53), modulating triglycerides (TG) release and favor its clearance (53) and deposition in white adipose tissue (WAT)
PubMed laboratory research record [PMID: 12168778] PubMed record related to this compound for laboratory literature review
