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Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB et al

Deficiency in mitochondrial complex I is associated with mutations in various structural subunits and assembly factors, resulting in a wide range of clinical manifestations, including LHON, infantile LS, MELAS, and epilepsy (56)

Scott Cancer Center, New Orleans, LA, USA), and grown in RPMI medium, 10% FBS, supplemented with 1% penicillin/streptomycin and 1% l-glutamine (All from Invitrogen, Carlsbad, CA, USA) in a humidified atmosphere of 5% CO 2 /95% air

After the 56-week treatment period, BMI standard deviation scores (BMI SDS) decreased by a mean of 0.23 in the liraglutide group, with no change in the placebo group