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Full-length HIF-3 can activate a distinct subset of hypoxia-responsive genes involved in metabolism, epithelialmesenchymal transition (EMT), and cellular survival, suggesting isoform-specific pro-tumorigenic functions under certain microenvironmental conditions
Bibcode:2014TPS....19..789A
76 FengQLiuZYuXHuangTChenJWangJet al
If injected subcutaneously, the micelles absorbed by the lymphatic system can aggregate in lymph nodes and kill tumor cells within the lymph nodes [63]
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