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Based on characteristic serological markers of HT, a prospective clinical trial demonstrated that Se supplementation reduced TPO-Ab titers and improved the quality of life of patients (56)

Environ Toxicol Pharmacol 37(2):638647

comparing liraglutide 1.2 mg/day + metformin 1000 mg BID with liraglutide 3 mg/day, the combination therapy was effective in reducing fasting glucose and insulin, HOMA-IR, and LDL cholesterol, while only the high dose of liraglutide resulted in a significant improvement of 120 min during OGTT glucose and insulin levels along with a higher weight loss [63]

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