They continue taking it to see if maintaining it has any beneficial effect
Other mechanisms of acetylcarnitine action Acetylcarnitine has been suggested to protect against oxidative stress through the induction of antioxidant genes and an increase in HO-1 (heme oxygenase 1) expression in vitro and in vivo [17, 18]
NAA exerts its function in a histone acetyltransferase P300/CBP-associated factor (PCAF)-dependent manner, leading to lamin A acetylation, impairing its interaction with Sun2 (Sad1 and Unc84 domain-containing protein 2) and subsequent lytic granules, from CD8 + T cells and NK cells, polarization and release [214]
Study inclusion consisted of meta-analyses of randomized controlled trials (RCTs), with subjects aged 18 years or older, using L-carnitine as the intervention, with a control or placebo group, a duration of follow-up of 2 weeks, and outcomes including lipid profiles and changes in TG, HDL-C, LDL-C, and TC