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Tesamorelin should not be used in children with open epiphyses, among whom excess GH and IGF-1 may result in linear growth acceleration and excessive growth
Gut microbiota-derived metabolites, particularly SCFAs like butyrate and acetate, play critical roles in maintaining metabolic and immune homeostasis, with dysbiosis-linked alterations implicated in the pathophysiology of numerous neurological disorders including stroke, AD, and PD (Mirzaei et al., 2021)
Over half of participants lost 20% or more of body weight
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