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It's possible that the rapid correction of high blood sugar induced by GLP-1 drugs rather than a toxic effect "could be a possible mechanism for vision loss," the 2025 study noted
Metformin is contraindicated in patients with an eGFR 4 years) is associated with vitamin B12 deficiency in 10-30% of patients, likely due to interference with calcium-dependent B12 absorption in the terminal ileum
Therefore, there's a lot of interest in developing drugs that can help combat obesity, but it's challenging to do so without any harmful side effects
The majority of the follow-on patenting covers methods of treating different indications, including obstructive sleep apnea, preventing or delaying the development of a cognitive disorder in a patient, as well as different dosing regimens for the treatment of diabetes and obesity
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