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This led to the assumption that the primary receptors mediating weight loss for this target class were AMYRs, yet, dual agonists are reported to have higher efficacy than AMYR selective agonists 2,10,11,12
However, the research authors emphasize that this does not indicate the shots can help a person lose weight, as there is no proof that a causal relationship exists
This therapy should not be used during pregnancy or breastfeeding
What we don't have is a Phase 3 randomized controlled trial showing that human patients on AOD-9604 heal fractures faster, achieve higher bone density, or return to function earlier than controls
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