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Curcumin formulations with enhanced bioavailability are thought to achieve therapeutic concentrations in plasma, which can reach dermal tissues to exert antiaging effects, particularly relevant for women experiencing estrogen decline [64]

Thus, experiments with ovariectomized (OVX) rats have shown a reduction in the anti-oxidant activity of superoxide dismutase (SOD) in the hippocampus, a process that contrasts with an increase in the pro-oxidant enzyme monoamine oxidase (MAO) in the same region (Huang and Zhang, 2010)

"But they can fail to find what symptoms patients are most concerned about

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