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According to USDA Agricultural Research Service data based on NHANES, approximately 6% of adults aged 60 and older in the United States are vitamin B12 deficient, defined as plasma B12 below 148 pmol/L (2009)

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The drug causes a reddish discoloration of the urine (chromaturia, which can look like blood in the urine), and of the skin

However, if you have a significant deficiency, certain digestive conditions, or issues with nutrient absorption, oral supplements might not be effective enough