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Method of Administration: Ozempic is administered by subcutaneous injection (under the skin)

The study was originally powered for 36 participants but randomized 24 because of budgetary and logistical constraints

In fact, one recent propensity-matched analysis of non-diabetic patients found that GLP-1 use was associated with a lower incidence of UTI, 8.8% compared to 13.3% in the control group

Key mechanisms include: Stimulation of collagen and elastin synthesis in fibroblasts Activation of lysyl oxidase for collagen cross-linking Enhanced production of glycosaminoglycans and decorin Modulation of metalloproteinase activity for controlled matrix breakdown The copper ion serves as an essential cofactor for enzymes involved in collagen synthesis and provides antioxidant protection through superoxide dismutase activation