These digestive symptoms are amongst the most commonly reported issues with GLP-1 receptor agonist injections, particularly during the initial weeks of treatment or after dose increases
During the Phase II study visits, participants consumed only standardized meals provided directly after blood draws at time points 0, 2.5, 16, 18, 20, and 24 h, as well as standardized meals taken home between study visits 2 and 3 of each pharmacokinetic intervention
Factors that support a diverse, healthy microbiomeincluding consuming fermented foods (yoghurt, kefir, sauerkraut), minimising unnecessary antibiotic use, and eating a varied, fibre-rich dietmay indirectly support metabolic health
We show that while the loss of certain host genes and pathways increased parasite survival, others had an inhibitory effect