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The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)
These data require further studies to be confirmed, but establish incretins as a key therapy for future clinical practice
Ozempic slims your weight
o On Day 61 or thereafter, if: No additional glycemic control is needed maintain the dosage at 4 mg orally once daily
