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Step #5: Monitor Blood Sugar Levels (If Applicable) If you were using semaglutide for diabetes management, keep track of your blood sugar levels to prevent spikes or crashes

Zepbound may affect how medicines are absorbed when taken around the same time

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In SELECT, a trial of adults with overweight or obesity and established cardiovascular disease but no diabetes, once-weekly semaglutide 2.4 mg cut the primary composite of cardiovascular death, nonfatal heart attack, or nonfatal stroke to 6.5% versus 8.0% on placebo a hazard ratio of 0.80, roughly a 20% relative reduction