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Black's development of propranol provided an important foundation for his development of cimetidine which he began to work on in earnest in 1964
As the pathogenesis of melasma is not entirely understood, there are prospects for the development of new therapeutic strategies that might act on the pathways that promote sustained pigmentation rather than merely decreasing melanin synthesis and removing melanin from the epidermis
(Springer, Cham: Springer Nature) 33745
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