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plantarum activates toll-like receptors (TLRs) signaling, leading to the translocation of the pivotal structural protein Zonula occludens-1 (ZO-1) to the tight junction domain in intestinal models (165)

Melittin suppresses inflammation and fibrosis in thioacetamide-induced liver fibrosis by blocking the NF-B signaling pathway

Note that most of this evidence comes from cell cultures and animal models, so it describes biological mechanisms rather than proven outcomes in people

Our results extend this role, positioning WWP-1 as a potential central regulator of lipid metabolism and aging through its interaction with NHR-49