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Medical weight loss intervention has been skyrocketing in recent years with many drugs on the market or in clinical trials, including incretin memetics or incretin receptor agonists such as Ozempic (semaglutide, SEMA) targeting glucagon-like peptide-1 (GLP-1) receptor (GLP1R) or dual agonist Mounjaro (tirzepatide) targeting GLP1R and glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR)