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The finding that older participants 45 were more likely to report no change in nicotine cravings (53.3%) may suggest that the behavioral effects of GLP-1 agonists are less pronounced in older populations, possibly due to age-related neurochemical changes or lower GLP-1 receptor sensitivity

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How your body makes and clears GABA: GABA is usually created from glutamate , an amino acid, using the enzyme glutamic acid decarboxylase (GAD)

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About 1 in 8 Americans takes a GLP-1 drug, according to a comprehensive 2025 poll by KFF, a health policy organization

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