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This process requires the involvement of protein disulfide isomerase (PDI), ER redox protein 1 (ERO1), and GRP78 chaperone protein

FOXO4-DRI peptide is selective in nature and exerts this potential action only on cells that have become dysfunctional over time due to aging, known as senescent cells

10.2337/dci18-0033 34 DavisJ.SinghS.SethiS.RoyS.MittraS.RayasamG.et al (2010)

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