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What to do if your pen warms beyond tolerance For unopened pens, the manufacturer guidance is to discard if storage temperature exceeded 86F (30C) for more than a brief period

As for weight loss, you'll probably start to see some real results after a couple of months, around 8 to 12 weeks, but the best outcomes happen when you stick with the treatment and make healthy changes to your lifestyle over several months

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Doses are typically increased gradually to reduce stomach-related side effects while finding the most effective dose for your weight loss