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Cardiovascular outcomes (TRIUMPH-Outcomes results expected 20282029) Cancer risk (very long-term monitoring needed) Effects in special populations (elderly, multiple comorbidities) Reassurance: Phase 2 participants stopping medication in extension showed reversibility of side effects, including dysesthesia

But, as always happens with big pharma blockbusters, the research community is busy exploring other possible applications for this class of compounds, with clinical trials underway or forming in cardiovascular disease, chronic kidney disease and obstructive sleep apnea

Spataru T, Birke RL

Home monitoring represents one of the most valuable tools for cardiovascular health tracking