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This process enhances endurance, reduces muscle fatigue, and supports weight management by ensuring fat is efficiently used as fuel rather than stored

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Additionally, adaptive thermogenesisa compensatory reduction in energy expenditure beyond what would be predicted by weight loss alonecan further slow metabolic rate, often by approximately 100-300 kcal/day, making continued weight reduction progressively more difficult

Treatment with brain natriuretic peptide prevents the development of cardiac dysfunction in obese diabetic db/db mice