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The tripeptide GHK has a strong affinity for copper(II) ions, forming a 1:1 complex that is the biologically active form
One cited study of 20 women found new collagen production in 70% of those treated with Cu-GHK after one month, compared with 50% for vitamin C and 40% for retinoic acid [2]
Oral supplements must first pass through the digestive tract, where a portion of the active compound can be degraded or poorly absorbed, especially if gastrointestinal issues are present
[2] Nitrous oxide overdose or overuse converts the active monovalent form of vitamin B 12 to the inactive bivalent form
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