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(38431210) Relative glutathione depletion may contribute: Glutathione deficiency up-regulates glutamylcysteine synthetase, which increases the level of glutamylcysteine
It helps the liver process and eliminate toxins by binding to harmful substances and making them water-soluble for easier elimination
Because IDO1 -associated inflammatory activation would be expected to increase, rather than decrease, the Kyn/Trp ratio [46,47,48], a one-tailed analysis was also performed
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