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The combined metabolic burden of both agents, particularly in the context of severe caloric restriction, could potentially affect: Reproductive hormone balance Glucose homeostasis Fluid and electrolyte balance Hypoglycaemia risk : For people with diabetes taking Wegovy alongside diabetes medications, there is an increased risk of hypoglycaemia
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Combination of oligofructose and metformin alters the gut microbiota and improves metabolic profiles, contributing to the potentiated therapeutic effects on diet-induced obese animals
Although numerous studies have evaluated the efficacy of GLP-1RAs, there remains a lack of comparative data on the gastrointestinal risk profiles of different GLP-1RAs
