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Surgery is not the first line of management and should be considered only if symptoms are severe or persistent, Sivaraman advised

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The concern is that persistent upper-GI symptoms can occasionally mask a Tier 3 condition like acute cholecystitis, which GLP-1 drugs do modestly increase in risk [4]

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Halloum W, Dughem YA, Beier D, Pellesi L (2024) Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review

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