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Additional studies in cynomolgus monkeys have confirmed the potent dose-dependent, weight-lowering effects of chronic GLP-1R/GcgR co-agonism [78], supporting the translational promise of this novel balanced agonism for obesity and type 2 diabetes
However, it is still sufficient to ensure rapid clearance of damaged erythrocytes and prevent their lytic cell death
Patient experiences in my opinion vary little between semaglutide and tirzepatide, until one gets to high doses where tirzepatide does appear to work slightly better
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