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165 In another study, a distinct senescence-like tetraspanin-8 (TSPAN8)+myofibroblastic CAF (myCAF) subgroup potentiates tumor stemness through SASP-associated factors IL-6 and IL-8, thereby promoting chemotherapy resistance in breast cancer
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Pyroptosis can be triggered by multiple upstream pathways, providing opportunities to selectively induce cell death in tumor cells [65]
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