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New mouse research suggests that while overall muscle mass may not drop as much as expected, muscle strength can still decline, highlighting a gap in understanding that needs urgent human studies

This complication has been assessed with multiple systematic reviews with meta-analyses demonstrating that while there may be an increased risk of acute pancreatitis with the DPP-4 inhibitors, there is no clear association with GLP1-RAs 16

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Gastroenterology 153 (3), 772786