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However, evidence is still emerging, and further well-designed randomized controlled trials are needed to develop the most effective and safe nutritional strategies for patients with FM

Before menstruation starts each month, the level of prostaglandins in the lining of the uterus increases

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Other common gastrointestinal effects include: Vomiting (5-24% of patients) Diarrhea (8-30% of patients) Constipation (10-24% of patients) Abdominal pain or discomfort (5-20% of patients) These side effects are typically most pronounced when initiating therapy or increasing doses, and often diminish over time as the body adjusts to the medication