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GSTs catalyse busulfan conjugation to GSH, yielding glutathionyl-tetrahydrothiophene (GS-THT +
ESA toxicity, however, was significantly suppressed by knockdown of ACSL1 , though other ACSL isoforms may also contribute
Acetaminophen (paracetamol) depletes glutathione during its own metabolism via the CYP450 pathway, and alcohol consumption already suppresses glutathione by 4050%
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