Intermittent fasting is a popular approach that involves alternating periods of eating and fasting, such as the 16:8 method (16 hours fasting, 8 hours eating window)
The result has been an explosion in demand, with roughly 40 million Americans having tried a GLP-1 for weight loss, according to a 2026 RAND report
The recommended dosages are based on the data from clinical trials for that specific use. For both types, higher doses may lead to negative side effects Increasing the dosage for both types of medications can come with negative side effects (nausea, vomiting, constipation, fatigue, loss of appetite and more)
Yilan Huang, [email protected] These authors share first authorship These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers