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A review of multiple studies concluded that individuals taking berberine reported a significant reduction in body weight and BMI
10.3892/ol.2021.13028 131 ZhouH.ShenQ.FuJ.JiangF.WangL.WangY
The primary concern at high doses (3g+) is the potential for elevated TMAO levels via gut bacteria conversion, though the clinical significance of this at moderate supplemental doses is debated
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