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Furthermore, dihydroethidine (DHE) staining showed that the proportion of DHE-positive cells after OGD treatment was higher than that in the control group, suggesting that the level of reactive oxygen species (ROS) was increased (Figure 3G)
AOD 9604 clinical trials showed a tolerability profile statistically indistinguishable from placebo
However, this study has certain limitations that warrant further investigation
If elevated liver enzymes are detected, healthcare providers may suggest modifying the glutathione dosage, and frequency, or exploring alternative treatments
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