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Patients should be counseled to seek immediate medical attention for severe, persistent abdominal pain radiating to the back, especially if accompanied by vomiting
In place of stability testing, 503A compounding pharmacies often rely on the following to establish the beyond-use date: Manufacturer recommendations Published clinical literature Limits set by the USP However, variances in formulation, container/closure system, and storage conditions between the medication the compounding pharmacy is altering and the reference drug that has undergone stability testing can result in an inaccurate beyond use date
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