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The researchers behind the 2010 trial theorized that its mechanism of action involves some mild aggravation of insulin, high amounts of which correspond with visceral fat accumulation.9 11 HIV and certain HIV treatments seem to facilitate the accumulation of visceral fat.12 It isnt clear why

During a Herxheimer reaction, toxins will be converted to compounds that can dissolve in water

And beyond the cost, there is the inconvenience of waiting for a replacement, the possibility of missing doses, and the disruption to a treatment plan that was finally working

Nadolsky K, Garvey WT, Agarwal M, Bonnecaze A, Burguera B, Chaplin MD, Griebeler ML, Harris SR, Schellinger JN, Simonetti J, Srinath R, Yumuk V