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Over time, this energy shortfall sets off a cascade of downstream effects: synaptic dysfunction, impaired protein clearance, neuroinflammation, and ultimately the accumulation of amyloid- and tau pathology [5]

For example: Type 2 diabetes: HbA1c result within past 90 days Hypertension: blood pressure readings on at least two separate dates Dyslipidemia: lipid panel within past 12 months Obstructive sleep apnea: sleep study report or CPAP compliance data A diagnosis code alone (ICD-10 E11.9 for type 2 diabetes) without supporting lab data triggers a denial

Plain-English explanation: KLOW is a product-category nickname

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