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Several of the non-coagulation associated gla residue containing proteins are matrix Gla protein (encoded by the MGP gene), osteocalcin [encoded by the BGLAP (bone gamma-carboxyglutamate protein) gene], growth arrest 6 (encoded by the GAS6 gene), and the proline-rich Gla domain proteins, PRRG1, PRRG2, PRRG3, and PRRG4

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Experts who spoke with BioSpace prior to the approval are hopeful that this small molecule will be a game-changer in terms of both diagnosis of and treatment for MASH