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Its core pathological feature is excessive accumulation of adipose tissue, accompanied by abnormal proliferation, differentiation, and metabolic dysfunction of adipocytes, which in turn induce a series of complications including insulin resistance, nonalcoholic fatty liver disease, and cardiovascular diseases
The most commonly reported GLP-1 side effects are gastrointestinal: nausea, vomiting, diarrhea, constipation, and indigestion
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