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Evidence and Effectiveness for Post-Surgical Weight Regain Clinical evidence supporting the use of GLP-1 receptor agonists for weight regain after bariatric surgery has expanded in recent years, though this remains an evolving area of research

Moreover, several clinical studies have identified elevated levels of numerous inflammatory markers, including CRP, TNF-, IL-1RA, sTNFR1, and sTNFR2, along with elevated serum NF-B levels, in patients with DPN compared to patients with T2DM without neuropathy, suggesting that patients with DPN exhibit a more pronounced inflammatory response (9698)

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Because weight reduction after bariatric surgery usually peaks after 24 months, the possible effect of LIRA in poor responders after laparoscopic sleeve gastrectomy may not have been obvious during this short period of administration [116]