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Here, the glutathione in mitochondria (mGSH) can be a triple threat
An engineered monomer binding-protein for -synuclein efficiently inhibits the proliferation of amyloid fibrils
It also alters melanin production from eumelanin (dark pigment) to phaeomelanin (lighter pigment), which contributes to its skin-brightening effect.(2) This mechanism explains why its often promoted as a depigmenting agent for issues like melasma, sun spots, and post-inflammatory hyperpigmentation
This work established that glutathione wasn't absorbed intact from dietary sources in meaningful amounts
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