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These models were fitted separately for each of the data sources (ie, CDM, MarketScan, and Medicare) and for each drug comparison (SGLT-2 inhibitors v DPP-4 inhibitors, GLP-1 receptor agonists v DPP-4 inhibitors, and SGLT-2 inhibitors v GLP-1 receptor agonists), for a total of nine propensity score models

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Using a Flexstation 3 plate reader, a baseline luminescence reading was acquired for 8 minutes at 37C, followed by stimulation with vehicle or 100 nM exendin-4 for Nb37 bystander assay, or with serial dilutions of exendin-4 starting from 1 M, 100 nM, 10 nM to 1 nM for 30 minutes for the mini-G s / mini-G q / -arrestin 2 recruitment assays

PMC 4953733