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Ozturk U, Yesil S, Goktug HN, et al

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As a widely used antihypertensive drug, losartan enhances vascular perfusion, thereby enhancing drug delivery and intratumoral invasion of immune effector cells and, on the other hand, enhances chemotherapy sensitivity by inhibiting IGF-1 signaling to reshape ovarian cancer and the microenvironment (140)

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Metformin typically continues unchanged

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