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The body continues to eliminate fat cells over the following weeks, providing gradual and long-lasting results
In a rodent model, a novel GLP-1R/GIPR/GCGR triple agonist, SAR441255, has been shown to promote weight loss and the maintenance of healthy blood glucose levels and is superior to the GLP-1R/GCGR dual agonist (Bossart et al., 2022)
Obesity While at the most basic level, obesity is caused by a person taking in more energy than they expend over a prolonged period, it is worth noting that humans have a complex neural mechanism regulating food intake, which is generally very effective at maintaining a balance between energy intake and expenditure
There's also a known effect that patients with diabetes are more prone to depression
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